廖新丽

个人简历：

1992-09 至1 996-08 biwn必赢化学系, 量子化学, 博士

1989-09 至 1992-07 厦门大学物理机电学院物理系, 无线电核磁共振, 硕士

1982-09 至 1986-07 厦门大学物理机电学院物理系, 光电子, 学士

科研与学术工作经历:

2019-08 至 2019-10 英国邓迪大学生命科学院核酸研究室访问学者

2018-04 至 2018-06 美国北卡罗来纳州大学教堂山分校药学院访问学者

2015-08 至 2015-10 美国麻省理工哈佛博德研究所访问科学家

2013-01 至 2016-12 主持国家自然科学基金项目“结核分支杆菌新药靶 RpsA 与 POA 作用阻断反式翻译的结构基础”

2010-03 至 2011-09 美国马里兰大学帕克分校生物分子科学实验室访问学者

1996-09 至今 biwn必赢, 助理教授、副教授

1986-07 至 1986-08 广西电力实验研究所电子室, 助理工程师

研究兴趣：
生物核磁共振技术及其在结构生物学研究中的应用，平衡态及非平衡态统计热力学的理论发展及应用，量子化学和分子动力学模拟。

近期主要代表论著：

1. 1. Fan, Shihui; Zhuang, Jie; Guo, Chenyun; Lin, Donghai; Liao, Xinli*; H-1, C-13, N-15 backb one and side-chain chemical shift assignments of the polyketide cyclase from Mycobacterium tuberc ulosis, Biomolecular NMR Assignments, 15(2): 397-402. (2021)

2. 2. Huang, Lin; Liao, Xinli; Li, Mengxiao; Wang, Jia; Peng, Xuemei; Wilson, Timothy J.; Lille y, David M. J.; Structure and folding of four putative kink turns identified in structured RNA s pecies in a test of structural prediction rules, Nucleic Acids Research, 49(10): 5916-5924. (2021)

3. 3. Xinli Liao; Shaokuan Zheng; Guoxing Lin; Pulsed field gradient signal attenuation of res tricted anomalous diffusions in plate, sphere, and cylinder with wall relaxation, Physical Review E, 101(012128): 1-14 (2020)

4. 4. Biling Huang; Shihui Fan; Yan Liu; Yufen Zhao; Donghai Lin; Xinli Liao*; Solution structu re and backbone dynamics for S1 domain of ribosomal protein S1 from Mycobacterium tuberculosis, European Biophysics Journal, 48(6): 491-501.(2019)

5. 5. Y. Fan, Y. Dai, M. Hou, H. Wang, H. Yao, C. Gu, D. Lin*, X. Liao*, Structural basis for ribosome protein S1 interaction with RNA in transtranslation of Mycobacterium tuberculosis. Biochem. Biophys. Resea. Commun. 487 268-273. (2017)

6. 6. J. Fu, B. Huang, D. Lin*, X.Liao* , Chemical shift assignments of Ribosomal protein S1 from Mycobacterium tuberculosis, Biomol NMR Assign 11:133–136.(2017)

7. 7. B. Huang, J. Fu, C. Guo, X.Wu, D. Lin, X.Liao*, ¹ H, ¹⁵N, ¹³C resonance assignments for pyrazinoic acid binding domain of ribosomal protein S1 from Mycobacterium tuberculosis,, Biomol NMR Assign 10:321–324. (2016).

8. 8. G..Lin, S. Zheng, X. Liao, Signal attenuation of PFG restricted anomalous diffusions in plate, sphere, and cylinder, J. Mag. Reson, 272 25–36. (2016)

9. 9. J. Yang, Y. Liu, J. Bi, Q. Cai, X. Liao, W. Li, C. Guo, Q. Zhang, T. Lin, Y. Zhao, H. Wang, J. Liu*, X. Zhang*, D. Lin*. Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide, Molecular Microbiology, DOI: 10.111/mmi.12892 (2014)

10. 10. Fu CP， Peng Y， Liao XL，Guo CY, Lin DH. H-1, C-13, N-15 backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form. Biomolecular NMR Assignments. Vol 7(2) 155-158 Oct. 2013

11. 11. Liao X, Long D, Li D, Bruschweiler R, Tugarinov V. Probing Side Chain Dynamics in Proteins by the Measurement of Nine Deuterium Relaxation Rates Per Methyl Group. J. Phys. Chem. B 116(1) :606-620 (2012).

12. 12. Liao X, Godoy-Ruiz R • Guo C, Tugarinov V. Simultaneous measurement of ¹H–¹⁵N and Methyl ¹Hm–¹³Cm residual dipolar couplings in large proteins. J Biomol NMR 51:191–198 (2011).

13. 13. Liao X, Tugarinov V, Selective detection of ¹³CHD₂ signals from a mixture of ¹³CH₃/¹³CH₂D/¹³CHD₂ methyl isotopomers in proteins, J. Magn. Reson. 209 (1): 101-107 (2011).

14. 14. Liao X, Jung P, Shuai J (2009) Global Noise and Oscillations in Clustered Excitable Media. Physical Review E. 79 (4) 041923,1-6.