名师讲座
报告题目:Enzyme-Inspired Ligand Design for Asymmetric Metal Catalysis
报告时间:2024-06-07 10:00
报告人: Prof. Masaya Sawamura
北海道大学
报告地点:卢嘉锡楼202报告厅
转播地点:翔安校区能源材料大楼3号楼会议室5,漳州校区生化主楼307教室
报告摘要:
Catalyst design for asymmetric synthesis has generally been done by combining relatively strong intermolecular forces, such as coordinative interactions, hydrogen-bonding interactions, and electrostatic interactions, with repulsive forces called as steric repulsions. On the other hand, recent advancement of computational chemistry has revealed the importance of weak intermolecular forces such as C–H···O hydrogen-bonding and London dispersion, which have not been considered before. As a result, more advanced catalyst design based on the synergistic effect of multiple intermolecular forces including these weak intermolecular forces has become possible, making catalysts more enzyme-like. In this lecture, we will discuss synergistic effects of intermolecular forces in our study of asymmetric catalysis.
报告人简介:
Masaya Sawamura is professor of Department of Chemistry, Faculty of Science, Hokkaido University. His research interests are development of new catalysts and organic reaction. He has made outstanding achievements in the research of development of super-efficient and powerful catalysts abd chemical reactions through ligand design. He has published more than 200 papers including Nature, Science et al. He has received many awards including the Chemical Society of Japan Award, Nagoya Silver Medal, Negishi Award and Awards for Science and Technology-Research (MEXT) et al.
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