学术报告：Synthesis and Assembly Biomimetic Heterogeneous Microcomponents on an Electromicrofluidic Platform

厦门大学谱学分析与仪器教育部重点实验室
biwn必赢
2016年8月16日

报告摘要：
Synthesis and assembly of multi-functional, heterogeneous, and encoded microcomponents, or building blocks, are essential to engineering hierarchical, complex, and three-dimensional structures. The elaborately organized architectures devise metamaterials that hold new physical properties unusual in nature or artificial tissues that reappear physiological functions by imitating natural and biological arrangements. Here we demonstrate synthesis and assembly of microcomponents by electrowetting-on-dielectric (EWOD) and dielectrophoresis (DEP) on a robotic electromicrofluidic platform. The platform is capable of (1) driving different droplets of hydrogel prepolymers before cross-linking, (2) arranging particles or cells in the droplets, and (3) forming microcomponents by cross-linking droplets in different shapes. In the presentation, we will demonstrate the synthesis and assembly of different hydrogel microcomponents containing different dyes and particles. The heterogeneous structures with cell adhesive GelMA (gelatin methacryloyl) and non-adhesive PEG-DA (Poly(ethylene glycol) diacrylate) surfaces are prepared for cell culture. The culture of fibroblasts NIH/3T3, neonatal mouse cardiomyocyte, and endothelia HUVEC on the engineered structures synthesized and assembled on the robotic electro-microfluidic platform will be reported.

报告人简历：


Shih-Kang Fan received the B.S. degree from National Central University, Taiwan, in 1996, and the M.S. and Ph.D. degrees from the University of California, Los Angeles (UCLA), USA in 2001 and 2003, respectively.

Between 2004 and 2009, he was an Assistant Professor with the Institute of Nanotechnology at National Chiao Tung University (NCTU), Taiwan. From 2009 to 2012, he was an Associate Professor in the Institute of Nanotechnology, the Department of Material Sciences and Engineering, and the Department of Mechanical Engineering at NCTU. From 2012 to 2015, he was an Associate Professor with the Department of Mechanical Engineering at National Taiwan University (NTU), Taiwan. He is now a Professor at NTU. His research interest focuses on electromicrofluidics.

Dr. Fan was a recipient of several young investigator awards in Taiwan, including the “TBF Chair in Biotechnology” from Taiwan Bio-Development Foundation and “Young Scholar’s Creativity Award” from Foundation for the Advancement of Outstanding Scholarship in 2014, the “Research Award for Junior Research Investigators” from Academia Sinica in 2012, and the “Ta-You Wu Memorial Award” from National Science Council in 2011.