报告题目: Using N, O to get Yes. Catalytic Amination for Small Molecule and Polymer Synthesis
报告人: Prof. Laurel L. Schafer
Associate Editor Organometallics
Department of Chemistry, University of British Columbia, Canada
时间: 2018年09月27日(星期四)上午10:30
地点: 厦门大学卢嘉锡楼202报告厅
嘉宾简介:
Prof. Schafer received her BSc from the University of Guelph in 1993, and her PhD from the University of Victoria in 1999 under the supervision of Prof. D. J. Berg. She then went on to the University of California-Berkley to complete an NSERC post-doctoral fellowship with Prof. T. D. Tilley. In 2001, she joined the University of British Columbia in Vancouver and has risen to the rank of full Professor and currently holds a Canada Research Chair in Catalyst Development (Tier II). The Schafer group has developed new families of N,O-chelated early transition metal complexes for atom-economic catalysis to prepare amines, heterocycles, enynes and biodegradable polymers. These catalysts can be used in tandem sequential reactions for the efficient synthesis of biologically active small molecules.
Research Interests: homogeneous catalysis using early transition metals, N,O-chelated organometallic complexes, hydroamination, small molecule synthesis
Selected Awards: AAAS Fellow (2015); Royal Society of Chemistry Fellow (2015); Clara Benson Award (2015); UBC Killam Award for Excellence in Mentoring (2013); Humboldt Research Award – LMU in Munich (2010)
Recent Publications:
[1] “Regio- and Stereoselective Hydroamination of Alkynes Using an Ammonia Surrogate – Synthesis of N-Silylenamines as Reactive Synthons.” J. Am. Chem. Soc. 2018, 140, 4973–4976.
[2] “Catalytic and Atom Economic Csp3 – Csp3 Bond Formation α-to Nitrogen. Alkyl Tantalum Ureates for Hydroaminoalkylation.” Angew. Chem. Int. Ed. 2018, 57, 3469–3472.
[3] “Ligand Effects and Kinetic Investigations of Sterically Accessible 2-Pyridonate Tantalum Complexes for Hydroaminoalkylation.” ACS Catal. 2017, 7, 6323–6330.
[4] “Amidate Complexes of Tantalum and Niobium for the Hydroaminoalkylation of Unactivated Alkenes.” ACS Catal. 2017, 7, 5921–5931.
[5] “1,3-N,O-Complexes of Late Transition Metals: Ligands with Flexible Bonding Modes and Reaction Profiles.” Chem. Soc. Rev. 2017, 46, 2913–2940
欢迎各位老师同学积极参加!