361005 biwn必赢化学生物学系 刘艳
电话:0592-2185610
传真:0592-2186292
E-mail: stacyliu@xmu.edu.cn
个人简历:
美国威斯康星大学麦迪逊分校, 药学院, 访问学者 (2012-2013)
biwn必赢化学生物学系 副教授 (2009-至今)
biwn必赢化学生物学系 助理教授 (2007-2009)
biwn必赢化学系 讲师 (2005-2007)
biwn必赢化学系生物有机化学专业 理学博士(2002-2005)
郑州大学化学系(清华大学化学系联合培养) 理学硕士(1999-2002)
郑州大学化学系 理学学士(1995-1999)
研究兴趣:
化学生物学及生物有机化学,主要包括:1)生命有机磷化学;2)生命起源与化学进化;3)生物有机质谱——糖肽的质谱检测新技术、新方法;4)有机活性小分子与生物大分子的相互作用研究。
近期主要代表论著:
在研项目:
1、福建省自然科学基金项目,No. 2017J01024,基于有机磷化学的稳定同位素寡糖衍生试剂的设计、合成及其在筛选血清中阿尔茨海默病早期诊断寡糖标志物的应用研究,主持。
2、国家自然科学基金项目,No. 21778042, 精氨酸磷酸化蛋白及其研究方法, 参与。
3、国家自然科学基金项目,No. 21772163,由白磷直接高效合成有机磷化合物的研究,参与。
发表论文:
[1]. Jianxi Ying, Rongcan Lin, Pengxiang Xu, Yile Wu, Yan Liu*, Yufen Zhao*, Prebiotic formation of cyclic dipeptides under potentially early Earth conditions, Scientific Reports, 2018, 8(936).
[2]. Hang Yuan, Xu Yang, Peng Chen, Yan Liu*, Guo Tang, Yufen Zhao*, Appraisal of an oligomerization behavior of unprotected carbohydrates induced by phosphorus reagent, SCIENCE CHINA Chemistry, 2018, 61: 243.
[3]. Yan Liu#, Yinbo Li#, Xiang Gao, Yongfei Yu, Xiaoxia Liu, Zhiliang Ji*, Yuan Ma, Yanmei Li, Yufen Zhao*, Evolutionary relationships between seryl histidine dipeptide and modern serine proteases from the analysis based on mass spectrometry and bioinformatics, Amino Acids, 2018, 50: 69.(# 共同一作)
[4]. Zhiqing Liu, Caihua Huang, Yan Liu*, Donghai Lin*, Yufen Zhao, NMR-based metabolomic analysis of the effects of alanyl-glutamine supplementation on C2C12 myoblasts injured by energy deprivation, RSC Adv., 2018, 8:16114.
[5]. Xu Yang, Jiepeng Gan, Hang Yuan, Peng Chen, Yan Liu*, Yuyang Jiang, Hongxia Liu, Yufen Zhao, MALDI MS-based analysis of oligosaccharides using 4-(diphenylphosphinyl) benzenamine as non-reductive amination derivatization reagent, International Journal of Mass Spectrometry, 2017, 417: 76.
[6]. Hang Yuan, Yile Wu, Wu Liu, Yan Liu*, Xiang Gao, Jinming Lin, Yufen Zhao, Mass spectrometry- based method to investigate the natural selectivity of sucrose as the sugar transport form for plants, Carbohydrate. Research, 2015, 407, 5.
[7]. Hang Yuan, Liu Liu, Jinping Gu, Yan Liu*, Meijuan Fang, Yufen Zhao*, Distinguishing of Isomeric Aldohexose-Ketohexose Disaccharides by Electrospray Mass Spcectrometry in Positive Mode, Rapid communication in Mass Spectrometry, 2015, 29, 2167.
[8]. Hang Yuan, Jianxi Ying, Peiran Deng, Peng Chen, Jinwen Shi, Yan Liu*, Xiang Gao*, Yufen Zhao, Specific interactions of leucine with disaccharides by electrospray ionization mass spectrometry: Application for rapid differentiation of disaccharide isomers combined with statistical analysis, Analyst, 2015, 140, 7965.[9]. Chen Peiyan, Du Xiujuan, Liu Yan*, Yufen Zhao, N-Terminal Acetylation of Phosphopeptides to Enhance the Interaction with SH2 Domain by Electrosprary Ion Trap Mass Spectrometry, International Journal of Peptide Research and Therapeutics, 2015,21,73.
[10]. Yulei Wang, Jiepeng Gan, Liu Liu, Hang Yuan, Yuxing Gao, * Yan Liu,* Yufen Zhao, Cs2CO3-Promoted One-Pot Synthesis of Alkynylphosphonates, -phosphinates, and -phosphine Oxides,Journal of Organic Chemistry, 2014, 79 (8):3678.
专著:
《前生源化学条件下磷对生命物质的催化与调控》,厦门大学出版社,2016年3月,赵玉芬、刘艳、高祥、许鹏翔。
授权发明专利
赵玉芬,袁航,刘艳,一种直链寡糖库及其制备方法,2014/06/04,中国, 专利号: CN2012102726343。
获奖情况
biwn必赢青年教师教学比赛校1等奖;
厦门大学“中国银行”“清源”等多项奖教金;
厦门大学首届“最受欢迎女教师”提名奖。