报告题目: The Application of Organometallic Electrochemistry in the
C–H functionalization and Carbon Dioxide Utilization
报告人: 梅天胜研究员
金属有机国家重点实验室, 中科院上海有机化学研究所
时间: 12月22日（周五）上午10:00
地点: 化四-112教室
报告摘要
Palladium-catalyzed C–H functionalization reactions have emerged as attractive tools for organic synthesis. Typically, these reactions require strong chemical oxidants, which convert organopalladium(II) intermediates into the PdIII or PdIV oxidation state to promote otherwise challenging C–O/C–C bond reductive elimination. However, previously reported oxidants possess significant disadvantages, including poor atom economy, high cost, and the formation of undesired byproducts. To overcome these issues, recently, we developed an electrochemical strategy that takes advantage of anodic oxidation of PdII to PdIII/PdIV to induce selective C–O/C–C reductive elimination (Figure 1).1-4 In the second part of my talk, catalytic carboxylation of allyl esters via electroreduction will be discussed.
Figure 1. Approaches to Pd(II)-catalyzed C–H functionalization via electrochemical oxidation.
References
1. Yang, Q. L.; Li, Y.-Q.; Ma, C.; Fang, P.; Zhang, X.-J.; Mei, T.-S. J. Am. Chem. Soc. 2017, 139, 3293.
2. Li, Y.-Q.; Yang, Q.-L.; Fang, P.; Mei, T.-S.; Zhang, D. Org. Lett. 2017, 19, 2905.
3. Ma, C.; Zhao, C.-Q.; Li, Y.-Q.; Zhang, L.-P.; Xu, X.-T.; Zhang, K.; Mei, T.-S.* Chem. Commun. 2017, 53, 12189.
4. Jiao, K.-J.; Zhao, C.-Q.; Fang, P.; Yang, Q.-L.; Li, Y.-Q.; Ma, C.; Fang, P.; Mei, T.-S. Tetrahedron Lett. 2017, 58, 797.
欢迎有兴趣的老师和同学参加！
固体表面物理化学国家重点实验室
biwn必赢
2017年12月17日
